Diagnosis of Small Cell Neuro-Endocrine Carcinoma Of Cervix
نویسنده
چکیده
There are several differences between neuroendocrine and other types of cervical cancer, in prognosis, diagnosis and treatment. Neuroendocrine cancer of the uterine cervix is a rare and aggressive disease. Small cell carcinoma is classified as a neuroendocrine tumor in the currently used World Health Organization histological classification of tumors of the uterine cervix (2003). Small-cell carcinoma is one of the most aggressive, poorly differentiated, and highly malignant neuroendocrine tumors and includes small-cell lung cancer and extrapulmonary small cell carcinoma (EPSCC). EPSCC is a rare disease, accounting for 2 % of all small cell carcinoma. Because of the rare nature of this disease, clinical trials for neuroendocrine cancer of the cervix are lacking. Social media and other innovative techniques may be useful to identify patients with this rare tumor. Patients may benefit from receiving care from centers with expertise in treating this disease. Treatment for neuroendocrine cervical cancer is usually more intensive than that for most other types of cervical cancer and therapy often utilizes multiple different modalities such as surgery, chemotherapy and radiation.
منابع مشابه
Small cell carcinoma of the uterine cervix with cerebellar metastasis: A special case report with literature review
Background: Small cell carcinoma of the uterine cervix is a highly malignant form of cancer in women, characterized by its high propensity for rapid extra-pelvic distant metastasis and poor prognosis. The best treatment strategy for this type of cancer is still controversial. Case presentation: We report here a case of small cell carcinoma of the uterine cervix treated by extensive total hyster...
متن کاملکارسینوماهای نورواندوکرین، بخش ایمونوهیستوشیمی انستیتو کانسر، 79-1375
Dispersed neuroendocrine system (D.N.S) consists of a wide variety of cells that are present in the central and peripheral nervous system and in many classic endocrine organs and different tissues such as respiratory and gastrointestinal tracts, skin, prostate, breast and also their neoplasm show neuroendocrine differentiation by electron microscopy, immunohistochemistry or biochemical techniqu...
متن کاملPrimary Clear Cell Carcinoma with no Diethylstilbestrol Exposure; Case Series
One of the rare neoplasms of cervix uteri and vagina is clear cell carcinoma; mostly in patients with a positive past medical history of intrauterine diethylstilbestrol (DES) exposure which reveals the importance of other unknown risk factors of gynecologic neoplasms. 2 Asian women referred to the gynecology-oncology department. The first one came with a complaint of prolonged vaginal discharge...
متن کاملفراوانی دیاتز توموری در اسمیرهای سیتولوژی کارسینوم گردن رحم در بیمارستان میرزا کوچکخان از سال 1375 تا 1383
Background: Tumor diathesis (TD) refers to the granular proteinaceous precipitates on the slide surface of cytologic (Pap) smears. Found in the background of smears from some, but not all, invasive carcinoma cases, TD is present in the majority of smears from large cell nonkeratinizing carcinoma. It is more pronounced than keratinizing SCC also is almost always present in small cell carcinoma. ...
متن کاملVerrucocus Carcinoma of Uterine Cervix
Verrucous carcinoma is a peculiar type of squamous cell carcinoma characterized by a clinicopathological behavior.This neoplasm is grossly cauliflower, warty, or parachute in shape, slowly growing and pushing the adjucent tissue without a definite invasion. Rarely causing metastasis. This tumor is radioresistant and the choice treatment is surgery. Histological features resemble the papilloma...
متن کامل